Ho, D.M., Guruharsha, K.G., and Artavanis-Tsakonas, S.  (2018).  The Notch Interactome: Complexity in Signaling Circuitry.  Adv. Exp. Med. Biol.  1066:125-140.

Engler, A., Rolando, C., Giachino, C., Saotome, I., Erni, A., Brien, C., Zhang, R., Zimber-Strobl, U., Radtke, F., Artavanis-Tsakonas, S., Louvi, A., and Taylor, V.  (2018).  Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone.  Cell Rep.  22(4):992-1002.

Huttlin, E.L., Bruckner, R.J., Paulo, J.A., Cannon, J.R., Ting, L., Baltier, K., Colby, G., Gebreab, F., Gygi, M.P., Parzen, H., Szpyt, J., Tam, S., Zarraga, G., Pontano-Vaites, L., Swarup, S., White, A.E., Schweppe, D.K., Rad, R., Erickson, B.K., Obar, R.A., Guruharsha, K.G., Li, K., Artavanis-Tsakonas, S., Gygi, S.P., and Harper, J.W.  (2017).  Architecture of the human interactome defines protein communities and disease networks.  Nature.  545(7655):505-509.

Ho, D.M., and Artavanis-Tsakonas, S.  (2016).  The Notch-Mediated Proliferation Circuitry.  Curr. Top. Dev. Biol.  116:17-33.

Stoiber, M.H., Olson, S., May, G.E., Duff, M.O., Manent, J., Obar, R., Guruharsha, K.G., Bickel, P.J., Artavanis-Tsakonas, S., Brown, J.B., Graveley, B.R., and Celniker, S.E.  (2015).  Extensive cross-regulation of post-transcriptional regulatory networks in Drosophila.  Genome Res.  25(11):1692-1702.

Ho, D.M., Pallavi, S.K., and Artavanis-Tsakonas, S.  (2015).  The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis.  Elife.  4:e05996.

Huttlin, E.L., Ting, L., Bruckner, R.J., Gebreab, F., Gygi, M.P., Szpyt, J., Tam, S., Zarraga, G., Colby, G., Baltier, K., Dong, R., Guarani, V., Vaites, L.P., Ordureau, A., Rad, R., Erickson, B.K., Wühr, M., Chick, J., Zhai, B., Kolippakkam, D., Mintseris, J., Obar, R.A., Harris, T., Artavanis-Tsakonas, S., Sowa, M.E., DeCamilli, P., Paulo, J.A., Harper, J.W., and Gygi, S.P.  (2015).  The BioPlex Network: A Systematic Exploration of the Human Interactome.  Cell  162(2):425-440.

Rhee, D.Y., Cho, D.Y., Zhai, B., Slattery, M., Ma, L., Mintseris, J., Wong, C.Y., White, K.P., Celniker, S.E., Przytycka, T.M., Gygi, S.P., Obar, R.A., and Artavanis-Tsakonas, S.  (2014).  Transcription factor networks in Drosophila melanogaster.  Cell Rep.  8(6):2031-2043.

Guruharsha, K.G., Hori, K., Obar, R.A., and Artavanis-Tsakonas, S.  (2014).  Proteomic analysis of the Notch interactome.  Methods Mol. Biol.  1187:181-192.

Hori, K., Sen, A., and Artavanis-Tsakonas, S.  (2014).  Genetic circuitry modulating notch signals through endosomal trafficking.  Methods Enzymol.  534:283-299.

Oh, P., Lobry, C., Gao, J., Tikhonova, A., Loizou, E., Manent, J., van Handel, B., Ibrahim, S., Greve, J., Mikkola, H., and Artavanis-Tsakonas, S., Aifantis, I.  (2013).  In vivo mapping of Notch pathway activity in normal and stress hematopoiesis.  Cell Stem Cell.  13(2):190-204.

Sen, A., Dimlich, D.N., Guruharsha, K.G., Kankel, M.W., Hori, K., Yokokura, T., Brachat, S., Richardson, D., Loureiro, J., Sivasankaran, R., Curtis, D., Davidow, L.S., Rubin, L.L., Hart, A.C., Van Vactor, D., and Artavanis-Tsakonas, S.  (2013).  Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy.  Proc. Nat'l. Acad. Sci. U.S.A.  110(26):E2371-2380.

Hori, K., Sen, A., and Artavanis-Tsakonas, S.  (2013).  Notch signaling at a glance.  J. Cell Sci.  126(Pt 10):2135-2140.

Šale, S., Lafkas, D., and Artavanis-Tsakonas, S.  (2013).  Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.  Nat. Cell Biol.  15(5):451-460.

Fleming, R.J., Hori, K., Sen, A., Filloramo, G.V., Langer, J.M., Obar, R.A., Artavanis-Tsakonas, S., and Maharaj-Best, A.C.  (2013).  An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling.  Development.  140(9):2039-2049.

Guruharsha, K.G., Obar, R.A., Mintseris, J., Aishwarya, K., Krishnan, R.T., Vijayraghavan, K., and Artavanis-Tsakonas, S.  (2012).  Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions.  Fly (Austin).  6(4):246-253.

Hori, K., Sen, A., Kirchhausen, T., and Artavanis-Tsakonas, S.  (2012).  Regulation of ligand-independent Notch signal through intracellular trafficking.  Commun. Integr. Biol.  5(4):374-376.

Guruharsha, K.G., Kankel, M.W., and Artavanis-Tsakonas, S.  (2012).  The Notch signalling system: recent insights into the complexity of a conserved pathway.  Nat. Rev. Genet.  13(9):654-666.

Pallavi, S.K., Ho, D.M., Hicks, C., Miele, L., and Artavanis-Tsakonas, S.  (2012).  Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila.  EMBO J.  31(13):2895-2907.

Louvi, A., and Artavanis-Tsakonas, S.  (2012).  Notch and disease: a growing field.  Semin. Cell Dev. Biol.  23(4):473-480.

Hori, K., Sen, A., Kirchhausen, T., and Artavanis-Tsakonas, S.  (2011).  Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal.  J. Cell Biol.  195(6):1005-1015.

Guruharsha, K.G., Rual, J.F., Zhai, B., Mintseris, J., Vaidya, P., Vaidya, N., Beekman, C., Wong, C., Rhee, D.Y., Cenaj, O., McKillip, E., Shah, S., Stapleton, M., Wan, K.H., Yu, C., Parsa, B., Carlson, J.W., Chen, X., Kapadia, B., VijayRaghavan, K., Gygi, S.P., Celniker, S.E., Obar, R.A., and Artavanis-Tsakonas, S.  (2011).  A protein complex network of Drosophila melanogaster.  Cell.  147(3):690-703.

Fre, S., Hannezo, E., Sale, S., Huyghe, M., Lafkas, D., Kissel, H., Louvi, A., Greve, J., Louvard, D., and Artavanis-Tsakonas, S.  (2011).  Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.  PLoS One.  6(10):e25785.

Arboleda-Velasquez, J.F., Manent, J., Lee, J.H., Tikka, S., Ospina, C., Vanderburg, C.R., Frosch, M.P., Rodríguez-Falcón, M., Villen, J., Gygi, S., Lopera, F., Kalimo, H., Moskowitz, M.A., Ayata, C., Louvi, A., and Artavanis-Tsakonas, S.  (2011).  Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease.  Proc. Nat'l. Acad. Sci. U.S.A.  108(21):E128-135.

Sun, Y., Klauzinska, M., Lake, R.J., Lee, J.M., Santopietro, S., Raafat, A., Salomon, D., Callahan, R., and Artavanis-Tsakonas, S.  (2011).  Trp53 regulates Notch 4 signaling through Mdm2.  J. Cell Sci.  124(Pt 7):1067-1076.

Sen, A., Yokokura, T., Kankel, M.W., Dimlich, D.N., Manent, J., Sanyal, S., and Artavanis-Tsakonas, S.  (2011).  Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling.  J. Cell Biol.  192(3):481-495.

Dimitriadi, M., Sleigh, J.N., Walker, A., Chang, H.C., Sen, A., Kalloo, G., Harris, J., Barsby, T., Walsh, M.B., Satterlee, J.S., Li, C., Van Vactor, D., Artavanis-Tsakonas, S., and Hart, A.C.  (2010).  Conserved genes act as modifiers of invertebrate SMN loss of function defects.  PLoS Genet.  6(10):e1001172.

Artavanis-Tsakonas, S., and Muskavitch, M.A.  (2010).  Notch: the past, the present, and the future.  Curr. Top. Dev. Biol.  92:1-29.

Kelly, D.F., Lake, R.J., Walz, T., and Artavanis-Tsakonas, S.  (2007).  Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless.  Proc. Nat'l. Acad. Sci. U.S.A.  104(23):9591-9596.

Bentley, A.M., Artavanis-Tsakonas, S., and Stanford, J.S.  (2008).  Nanocourses: a short course format as an educational tool in a biological sciences graduate curriculum.  CBE Life Sci. Educ. 7(2):175-183.

Fleming, R.J.,Purcell, K., and Artavanis-Tsakonas, S.  (1997).  The Notch receptor and its ligands.  Trends Cell Biol. 7(11):437-441.

Mazzone, M., Selfors, L.M., Albeck, J., Overholtzer, M., Sale, S., Carroll, D.L., Pandya, D., Lu, Y., Mills, G.B., Aster, J.C., Artavanis-Tsakonas, S., and Brugge, J.S.  (2010).  Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells.  Proc Natl Acad Sci U S A. 107(11):5012-7.

Lake, R.J., Grimm, L.M., Veraksa, A., Banos, A., and Artavanis-Tsakonas, S.  (2009).  In vivo analysis of the Notch receptor S1 cleavage.  PLoS One 4(8):e6728.

Fre, S., Pallavi, S.K., Huyghe, M., Laé, M., Janssen, K.P., Robine, S., and Artavanis-Tsakonas, S., Louvard, D.  (2009).  Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine.  Proc Natl Acad Sci U S A. 106(15):6309-14.

Hurlbut, G.D., Kankel, M.W., and Artavanis-Tsakonas, S.  (2009).  Nodal points and complexity of Notch-Ras signal integration.  Proc Natl Acad Sci U S A. 106(7):2218-23.

Chang, H.C., Dimlich, D.N., Yokokura, T., Mukherjee, A., Kankel, M.W., Sen, A., Sridhar, V., Fulga, T.A., Hart, A.C., Van Vactor, D., and Artavanis-Tsakonas, S.  (2008).  Modeling spinal muscular atrophy in Drosophila.  PLoS One 3(9):e3209.

Arboleda-Velasquez, J.F., Zhou, Z., Shin, H.K., Louvi, A., Kim, H.H., Savitz, S.I., Liao, J.K., Salomone, S., Ayata, C., Moskowitz, M.A., and Artavanis-Tsakonas, S.  (2008).  Linking Notch signaling to ischemic stroke.  Proc Natl Acad Sci U S A. 105(12):4856-61.

Kankel, M.W., Hurlbut, G.D., Upadhyay, G., Yajnik, V., Yedvobnick, B., and Artavanis-Tsakonas, S.  (2007).  Investigating the genetic circuitry of mastermind in Drosophila, a Notch signal effector.  Genetics 177:2493-505.

Kelly, D.F., Lake, R.J., Walz, T., and Artavanis-Tsakonas, S.  (2007).  Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless.  Proc Natl Acad Sci U S A. 23:9591-6.

Hurlbut, G.D., Kankel, M.W., Lake, R.J., and Artavanis-Tsakonas, S.  (2007).  Crossing paths with Notch in the hyper-network.  Curr Opin Cell Biol. 19(2):166-175.

Klinakis, A., Szabolcs, M., Politi, K., Kiaris, H., Artavanis-Tsakonas, S., and Efstratiadis, A.  (2006).  Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.  Proc Natl Acad Sci U S A. 19(2):166-175.

Louvi, A., Arboleda-Velasquez, J., and Artavanis-Tsakonas, S.  (2006).  CADASIL: a critical look at a Notch disease.  Dev Neurosci. (28): 5-12.

Mourikis, P., Hurlbut, G.D., and Artavanis-Tsakonas, S.  (2006).  Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila.  Proc Natl Acad Sci U S A. (5):1307-12.

Louvi, A., and Artavanis-Tsakonas, S.  (2006).  Notch signalling in neural development. Nature Rev Neurosci. (2): 93-102.  Nature Rev Neurosci. (2): 93-102.

Mukherjee, A., Veraksa, A., Bauer, A., Rosse, C., Camonis, J., and Artavanis-Tsakonas, S.  (2005).  Regulation of Notch signalling by non-visual beta-arrestin.  Nature Cell Biol. (12): 1191-201.

Fre, S., Huyghe, M., Mourikis, P., Robine, S., Louvard, D., and Artavanis-Tsakonas S.  (2005).  Notch signals control the fate of immature progenitor cells in the intestine.  Nature 435: 964-968.

Veraksa, A., Bauer, A., and Artavanis-Tsakonas, S.  (2005).  Analyzing protein complexes in Drosophila with Tandem Affinity Purification-mass spectrometry.  Dev. Dyn. 232: 827-834.

Moberg, K.H., Mukherjee, A., Veraksa, A., Artavanis-Tsakonas, S., and Hariharan, I.K.  (2004).  The Drosophila F Box Protein Archipelago Regulates dMyc Protein Levels In Vivo.  Curr. Biol. 14: 965-974.

Artavanis-Tsakonas S.  (2004).  Accessing the Exelixis collection.  Nat Genet. 36: 207

Beltran, S., Blanco, E., Serras, F., Perez-Villamil, B., Guigo, R., Artavanis-Tsakonas S., and Corominas, M.  (2003).  Transcriptional network controlled by the trithorax-group gene ash2 in Drosophila melonogaster.  Proc Natl Acad Sci U S A 100: 196-200.

Grandbarbe, L., Bouissac, J., Rand, M., Hrabe de Angelis, M., Artavanis-Tsakonas S., and Mohier, E.  (2003).  Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process.  Development 130: 1391-1402.

Mishra-Gorur, K., Rand, M.D., Perez-Villamil, B., and Artavanis-Tsakonas S.  (2002).  Down-regulation of Delta by proteolytic processing.  J Cell Biol 159: 313.324.

Matsuno K., Ito M., Hori K., Miyashita F., Suzuki S., Kishi N., Artavanis-Tsakonas S., and Okano H.  (2002).  Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling.  Development 129: 1049-1059.

Kiaris H., Schally A.V., Busto R., Halmos G., Artavanis-Tsakonas S., and Varga J.L.  (2002).  Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs.  Proc Natl Acad Sci U S A 99: 3293-3298.

Kishi N., Tang Z., Maeda Y., Hirai A., Mo R., Ito M., Suzuki S., Nakao K., Kinoshita T., Kadesch T., Hui C., Artavanis-Tsakonas S., Okano H., and Matsuno K.  (2001).  Murine homologs of Deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.  Int. J. Dev. Neurosci. 19: 21-35.

Wu, L., Aster, J.C., Blacklow, S.C., Lake, R., Artavanis-Tsakonas, S., and Griffin, J.D.  (2000).  MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors.  Nat Genet. 26: 484-489.

Rand, M.D., Grimm, L.M., Artavanis-Tsakonas, S., Patriub, V., Blacklow, S.C., Sklar, J., and Aster, J.C.  (2000).  Calcium depletion dissociates and activates heterodimeric Notch receptors.  Mol. Cell Biol. 20: 71825-1835.

Hing, H.K., Bangalore, L., Sun, X., and Artavanis-Tsakonas, S.  (1999).  Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling.  Eur. J. Cell Biol. 78: 690-697.

Sestan, N., Artavanis-Tsakonas, S., and Rakic, P.  (1999).  Contact-dependent inhibition of cortical neurite growth mediated by notch signaling.  Science 286: 741-746.

Purcell, K., and Artavanis-Tsakonas, S.  (1999).  The developmental role of warthog, the Notch modifier encoding Drab6.  J. Cell Biol. 136: 731-740.

Cornell, M., Evans, D.A., Mann, R., Fostier, M., Flasza, M., Monthatong, M., Artavanis-Tsakonas, S., and Baron, M.  (1999).  The Drosophila melanogaster suppressor of Deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase.  Genetics 152: 567-576.

Gray, G.E., Mann, R.S., Mitsiadis, E., Henrique, D., Carcangiu, M,L., Banks, A., Leiman, J., Ward, D., Ish-Horowitz, D., and Artavanis-Tsakonas, S.  (1999).  Human ligands of the Notch receptor.  Am. J. Pathol. 154: 785-794.

Qi, H., Rand, M.D., Wu, X., Sestan, N., Wang, W., Rakic, P., Xu, T., and Artavanis-Tsakonas, S.  (1999).  Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian.  Science 283: 91-94.